The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 1990

Filed:

Jun. 08, 1987
Applicant:
Inventors:

Bonita J Rup, St. Louis, MO (US);

Larry E Kahn, St. Louis, MO (US);

Assignee:

G. D. Searle & Co., Chicago, IL (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C07K / ; A61K / ;
U.S. Cl.
CPC ...
530387 ; 43524027 ; 435948 ; 435 7021 ; 436513 ; 424 858 ; 530809 ; 935104 ; 935107 ;
Abstract

The present invention is directed to monoclonal antibodies and hybridomas which produce them, which react with IgE when it is unbound and thereby inhibit IgE binding to mast cells, and react with IgE when it is bound to the B-cell FcE receptor, but do not react with IgE when it is bound to the mast cell FcE receptor.


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