The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 26, 1990

Filed:

Dec. 04, 1989
Applicant:
Inventors:

Armando Vega-Noverola, Barcelona, ES;

Jose M Soto, Barcelona, ES;

Fernando P Noguera, Barcelona, ES;

Jacinto M Mauri, Barcelona, ES;

Robert G Spickett, Tibidabo, ES;

Assignee:

Fordonal, S.A., Madrid, ES;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514161 ; 514299 ; 514304 ; 514305 ;
Abstract

A method of treating anxiety including administering to a person to be treated an effective amount of compounds of the general formula: ##STR1## wherein the various substituents are defined hereinbelow have pharmacological properties rendering them useful as antiemetic agents with reduced undesirable side-effects or as anxiolytic agents. Various methods are described for their preparation involving formation of the amide link, etherification of the 2-hydroxy derivative, introducing the R.sup.5 CH.sub.2 group on the N-unsubstituted azabicyclooctane or nonane or, for 4-amino compounds, by hydrolysing a 4-acylamino derivative.


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