The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 1990
Filed:
Mar. 03, 1989
Aaron H Heifetz, Columbia, MD (US);
Richard A Wolfe, Ellisville, MO (US);
James A Braatz, Beltsville, MD (US);
Narender P Luthra, Columbia, MD (US);
W. R. Grace & Co.-Conn., New York, NY (US);
Abstract
Modified hydrophilic prepolymers and polymers are disclosed wherein the prepolymers and polymers are characterized by cell growth enhancement, and, in some instances, antibody production stimulation. Isocyanate-capped oxyethylene-based prepolymers are modified by reaction with a compound having at least one isocyanate (NCO) reactive group. Preferably, the NCO reactive group is a sulfhydryl group, an amino group or a carboxyl group, in quantities sufficient to modify at least a portion of the isocyanate groups of the prepolymer. The prepolymer and polymer also express a free functional group, preferably an amino, sulfonic acid or a sulfhydryl. When the free functional group is sulfhydryl or sulfonic acid, antibody production stimulation, as well as cell growth enhancement, is observed.