The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 1990
Filed:
Apr. 08, 1988
Applicant:
Inventors:
Robert Halenbeck, San Rafael, CA (US);
Kriston Koths, El Cerrito, CA (US);
Cynthia Cowgill, Berkeley, CA (US);
Walter J Laird, Pinole, CA (US);
Assignee:
Cetus Corporation, Emeryville, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K / ;
U.S. Cl.
CPC ...
530351 ; 530395 ; 530404 ; 530402 ; 530405 ; 530412 ; 530413 ; 530414 ; 530415 ; 530416 ; 530416 ; 530418 ; 530419 ; 530422 ; 530820 ; 530825 ; 435 695 ; 435 696 ; 435 712 ;
Abstract
A process for recovering dimeric, biologically active CSF-1 from bacterially expressed recombinant CSF1 genes is described. The process comprises recovery of the solubilized monomeric form, followed by dimerization under refolding conditions and further purification of the dimer. Heterodimers may also be produced by this process.