The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 29, 1990

Filed:

Jun. 08, 1988
Applicant:
Inventors:

Seiji Shibahara, Machida, JP;

Yukiko Takahashi, Kawasaki, JP;

Yuji Matsuhashi, Yokohama, JP;

Mitsugu Hachisu, Yokohama, JP;

Shinichi Kondo, Yokohama, JP;

Tomio Takeuchi, Shinagawa, JP;

Takaaki Aoyagi, Fujisawa, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; A61K / ;
U.S. Cl.
CPC ...
514423 ; 548540 ;
Abstract

As new compounds are provided a class of derivatives of actinonin represented by the general formula ##STR1## where R is a hydrogen or a lower alkyl group, which can exhibit the enzyme-inhibitory activities to a limited range of peptidases and show a remarkable enzyme-specificity, and which are effective to treat a cycloheximide-induced experimental amnesia in mice and are expectable to be useful to treat an amnesia in a mammalian animal, including human.


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