The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 1990
Filed:
Aug. 15, 1989
Applicant:
Inventors:
Tamotsu Eguchi, Machida, JP;
Takashi Oshiro, Machida, JP;
Yukihiro Kuge, Osakasayama, JP;
Kenichi Mochida, Hiratsuka, JP;
Takayuki Uwajima, Machida, JP;
Assignee:
Kyowa Hakko Kogyo Co., Ltd., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ;
U.S. Cl.
CPC ...
435106 ; 435119 ; 435177 ; 435191 ; 43525233 ; 435280 ; 435320 ; 435814 ; 435849 ;
Abstract
The invention relates to a process for producing L(-)-tetrahydrofolic acid which comprises allowing dihydrofolate reductase to act upon dihydrofolic acid in the presence of (1) NADP or NADPH, and (2) glucose and glucose dehydrogenase. L(-)-tetrahydrofolic acid is useful as the intermediate for L(-)-leucovarin.