The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 15, 1990

Filed:

Apr. 19, 1989
Applicant:
Inventors:

Ralph N Harris, III, Redwood City, CA (US);

Clifford D Bedford, Silver Spring, MD (US);

Dane A Goff, Menlo Park, CA (US);

Duane E Hilmas, Worthington, OH (US);

Robert A Howd, Rancho Cordova, CA (US);

Richard A Kenley, Libertyville, IL (US);

Gary A Koolpe, Mountain View, CA (US);

Robert O Pick, Walkersville, MD (US);

Assignee:

SRI International, Menlo Park, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514341 ; 514101 ; 514397 ; 514400 ; 546278 ; 548336 ; 548343 ;
Abstract

A therapeutically effective class of low toxicity aldoxime-substituted functionalized imidazolium compounds and compositions is disclosed which is effective in the treatment of living species poisoned by organophosphorus chemicals which inactivate the enzyme acetylcholinesterase. In vivo administration of therapeutically effective amounts of these aldoxime-substituted imidazolium derivatives has been found to save mammals having inhibited acetylcholinesterase due to injection with lethal dosages of Soman.


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