The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 08, 1990

Filed:

Aug. 24, 1988
Applicant:
Inventors:

Alan E Walts, Brookline, MA (US);

Ellen M Fox, Cranston, RI (US);

Assignee:

Genzyme Corporation, Boston, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; C12P / ; C07P / ; C12N / ;
U.S. Cl.
CPC ...
435117 ; 435280 ; 435157 ; 435123 ; 435132 ; 435197 ; 435176 ; 435177 ; 435198 ; 435174 ; 435180 ;
Abstract

A method of resolving glycidyl esters to high enantiomeric excess involves fractionation of hydrolytic enzymes (e.g. lipases) to prepare biocatalysts with high enantioselectivity, and using these catalysts to selectively hydrolyze one enantiomer of the glycidyl esters. Also a method for fractionation includes stirring an aqueous solution of the enzyme with a solid inert adsorbent to provide an adsorbed and non-adsorbed enzyme fraction, where the non-adsorbed fraction displays a higher enantioselectivity than the crude non-fractionated enzyme. Also a composition composed of a glycidyl ester is obtained with an enantiomeric excess of greater than or equal to 97%.


Find Patent Forward Citations

Walts, Alan. (1990). Resolution of glycidyl esters to high enantiomeric excess (U.S. Patent No. 4923810). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/4923810

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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