The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 08, 1990
Filed:
Mar. 23, 1988
Dietrich Seidel, Gottingen, DE;
Heinrich Wieland, Waake, DE;
Gerhard Rosskopf, Fuldabruck-Dornhagen, DE;
Dieter Rath, Melsungen, DE;
B. Braun-SSC AG, Emmenbrucke, CH;
Abstract
Processes are described for the selective extracorporeal precipitation of low density lipoproteins or beta-lipoproteins from whole serum or plasma, wherein a treating agent comprising heparin or a polyanion, such as dextran sulfate or sodium-phosphorus tungstate, in a buffer is added to the whole serum or plasma and the beta-llipoprotein-complex which thereupon forms with the treating agent is precipitated at the isoelectric point at a pH value in the range of from about 5.05 to about 5.25, and is then separated. Optionally, the precipitate or respecively the filtrate is further analyzed for diagnostic purposes. When heparin is employed, the process may be employed therapeutically. Apparatus is described for the continuous therapeutic practice of such a process, employing heparin, including means for flushing to reduce clogging of the filter employed to separate the precipitated lipoprotein-complex.