The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 01, 1990

Filed:

Oct. 13, 1987
Applicant:
Inventors:

Takashi Kamiya, Ibaraki, JP;

Toshihiko Naito, Ibaraki, JP;

Shigeto Negi, Ibaraki, JP;

Yuuki Komatu, Ibaraki, JP;

Yasunobu Kai, Ibaraki, JP;

Takaharu Nakamura, Chiba, JP;

Isao Sugiyama, Ibaraki, JP;

Yoshimasa Machida, Ibaraki, JP;

Seiichiro Nomoto, Ibaraki, JP;

Kyosuke Kitoh, Ibaraki, JP;

Kanemasa Katsu, Ibaraki, JP;

Hiroshi Yamauchi, Ibaraki, JP;

Assignee:

Eisai Co., Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ;
U.S. Cl.
CPC ...
514202 ; 514203 ; 514204 ; 514206 ; 540222 ; 540225 ; 540226 ;
Abstract

A 3-propenylcephem derivative of the following formula: ##STR1## wherein R.sub.1 represents a fluoro-substituted lower alkyl group or a cyano-substituted lower alkyl group, and A represents a cyclic or an acylic ammonio group, or a pharmaceutically acceptable salt thereof, exhibiting excellent anti-bacterial activities against both Gram-positive bacteria and Gram-negative bacteria; Process for the preparation thereof; Anti-bacterial composition; Intermediate for the 3-propenylcephem derivative; and Process for the preparation of the intermediate.


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