The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 1990
Filed:
Jun. 16, 1987
Applicant:
Inventors:
Nicholas Catsimpoolas, Newton Centre, MA (US);
Ann L Griffith, Newton Centre, MA (US);
Robert S Sinn, New York, NY (US);
Assignees:
Trustees of Boston University, Boston, MA (US);
Angio-Medical Corp., New York, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A01N / ; A01N / ; C07J / ;
U.S. Cl.
CPC ...
514 25 ; 514 75 ; 514 53 ; 536-60 ; 536-41 ; 558 38 ; 558 48 ; 568622 ; 568608 ; 549478 ; 260403 ; 564291 ;
Abstract
A method for enhancing angiogenesis and/or blood vascular perfusion in mammals by administering a pharmacologically effective amount of specific angiogenically active non-ionic, anionic, cationic and zwitterionic amphiphilic compounds. An angiogenically effective amount of the angiogenically active compound digitonin is in the range of at least 1.25 microgram to at least 200 microgram of digitonin. The range including enhancement of vascular perfusion is up to 50 mg of digitonin.