The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 24, 1990
Filed:
Oct. 19, 1987
Applicant:
Inventors:
Wolfgang Feller, Melsungen, DE;
Norbert Macht, Melsungen, DE;
Johannes G Bottrich, Kirtorf-Lehrbach, DE;
Assignee:
Other;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ; A61K / ;
U.S. Cl.
CPC ...
530385 ; 514-6 ; 424101 ;
Abstract
The invention relates to stroma-free blood substitutes, which are characterized in that fragments, prepared in a per se known manner, of sulfated glycosaminoglycans are covalently linked with hemoglobin to form products the oxygen binding property of which may be adjusted to be within the range of from 2.66 kPa (20 mmHg) to 10.66 kPa (80 mmHg), and preferably to within the range of from 4.79 kPa (36 mmHg) to 9.33 kPa (70 mmHg) by pre-determining the ratio of hemoglobin to glycosaminoglycan fragment, and to a process for preparing blood substitutes.