The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 1990
Filed:
Aug. 21, 1986
Applicant:
Inventors:
Howard Green, Brookline, MA (US);
Vann Barrandon, Boston, MA (US);
Assignee:
President and Fellows of Harvard College, Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q / ; G01N / ;
U.S. Cl.
CPC ...
435 29 ; 4382402 ; 436 63 ;
Abstract
Compounds are assayed for ability to promote epidermal cell growth and migration. The assay methods feature growing 'megacolonies', which are large colonies having a surface area greater than 1 cm.sup.2, and measuring growth during the linear growth phase, or measuring radial expansion during the exponential growth phase. These measurment allow comparison of growth factors and provide good estimates of the biological activity of such factors. A method of producing megacolonies and the megacolonies so produced are also disclosed.