The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 10, 1990

Filed:

Aug. 27, 1987
Applicant:
Inventors:

Goro Asato, Titusville, NJ (US);

Donald J France, Pennington, NJ (US);

Assignee:

American Cyanamid Company, Stamford, CT (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514450 ; 549264 ;
Abstract

The present invention relates to novel 23-imino derivatives of LL-F28249.alpha., .beta., .gamma., .delta., .epsilon., .zeta., .theta., .iota., and .lambda. compounds. These LL-F28249 compounds (collectively) are isolates from the fermentation broth of Streptomyces cyaneogrisesu subspecies noncyanogenus having deposit accession number NRRL 15773. The precursor 23-oxo compounds are prepared by selectively oxidizing suitably protected 23-hydroxy compounds of LL-F28249 components using oxidizing agents. Subsequently, the 23-oxo compounds are converted to the 23-imino compounds. These novel compounds have potent anthelmintic, insecticidal, ectoparasiticidal, nematicidal and acaricidal activity. Compositions containing these 23-oxo and 23-imino derivatives of LL-F28249 also are described herein.


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