The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 1990

Filed:

May. 06, 1988
Applicant:
Inventors:

Patrick Couvreur, Wavre, BE;

Michel Roland, Brussels, BE;

Peter Speiser, Forch, CH;

Assignee:

N. V. Sopar S.A., Sart-Dames-Avelines, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
424501 ; 424-11 ; 424-71 ; 424486 ; 424487 ; 42721331 ; 42721334 ; 42840222 ; 514965 ; 526297 ;
Abstract

Process for the preparation of submicroscopic particles formed of a polymerized alkyl cyanoacrylate and containing a biologically active substance. At least one alkyl cyanoacrylate, in which the term 'alkyl' denotes an alkyl radical having 1 to 12 carbon atoms, is added, with stirring, to pure water or to an aqueous solution or aqueous colloidal solution of an acid and/or of another water-soluble substance, and the stirring is continued until substantially all the alkyl cyanoacrylate has been converted to submicroscopic particles formed of polyalkyl cyanoacrylate; a biologically active substance is introduced into the reaction medium before the introduction of the monomer or after formation of the submicroscopic particles. The submicroscopic particles are useful as carriers for substances such as medical substances or products for diagnosis.


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