The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 27, 1990

Filed:

Aug. 07, 1986
Applicant:
Inventors:

Robert C Kelly, Augusta, MI (US);

Martha A Warpehoski, Kalamazoo, MI (US);

Wendell Wierenga, Kalamazoo, MI (US);

Assignee:

The Upjohn Company, Kalamazoo, MI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
548421 ; 544355 ; 544405 ; 546168 ; 546271 ; 548181 ; 548237 ; 548300 ; 548433 ;
Abstract

1,2,8,8a-Tetrahydrocyclopropa[3]pyrrolo(3,2-e)indol-4(5H)-ones, and related compounds of formulas I and intermediate therefor II ##STR1## wherein R.sub.2, R.sub.2 ', R.sub.3, R.sub.5, R.sub.50 and X are as defined in the specification, e.g., (7bR,8aS)-1,2,8,8a-tetrahydro-7-methyl-2-[[5-(((1H-indol-2-yl)carbonyl)ami no)-1H-indol-2-yl]carbonyl]cyclopropa[pyrrolo[3,2-e]indol-4(5H)-one (U-71,184), as purified, and its racemic form (U-68,415), and related compounds, are useful as ultraviolet light absorbers and as antibacterials. The lead compounds are useful as antitumor drug compounds in standard laboratory animal tests.


Find Patent Forward Citations

Kelly, Robert. (1990). 1,2,8,8a-tetrahydrocyclopropa(c)pyrrolo(3,2-e)-indol-4-(5h)-ones and (U.S. Patent No. 4912227). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/4912227

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