The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 27, 1990

Filed:

Dec. 22, 1988
Applicant:
Inventors:

Erno Mohacsi, Summit, NJ (US);

Jay P O'Brien, Cedar Grove, NJ (US);

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514211 ; 540488 ;
Abstract

(+)-Cis compounds of the formula ##STR1## wherein R is lower alkyl; R.sub.1 is ##STR2## wherein R.sub.3 is pyridyl, ##STR3## or phenyl unsubstituted or substituted by up to 3 substituents selected from the group consisting of hydroxy, halogen, lower alkoxy, and lower alkanoyloxy; (-)cis enantiomers, and (.+-.)-cis racemates thereof; or pharmaceutically acceptable acid addition salts thereof are described.


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