The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 1990
Filed:
Oct. 21, 1988
Applicant:
Inventors:
Arnold L Newman, Kensington, MD (US);
William D Stanbro, Columbia, MD (US);
Assignee:
The Johns Hopkins University, Baltimore, MD (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12M / ;
U.S. Cl.
CPC ...
435291 ; 356364 ; 250225 ;
Abstract
A differential polarimeter is disclosed for detecting changes in optical rotation between a test cell and reference cell. The test cell contains a fluid sample exposed to an analyte specific enzyme; the reference cell contains a fluid sample not exposed to the enzyme. To enhance the sensitivity of the system a phase sensitive differential polarimetric technique is taught. In this technique, the phase difference between two resulting sinewave voltages is a measure of analyte concentration.