The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 27, 1990

Filed:

Mar. 13, 1989
Applicant:
Inventors:

William Heggie, Barreiro, PT;

Philip R Page, Sintra, PT;

Ivan Villax, Lisboa Codex, PT;

Indira Ghatak, London, GB;

Michael Hursthouse, Essex, GB;

Assignee:

Plurichemie Anstalt, Liechtenstein, LI;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07B / ; C07C / ; B01J / ;
U.S. Cl.
CPC ...
552207 ; 502166 ; 556 21 ;
Abstract

The present invention refers to complexes prepared by reacting rhodium trinitrate with a suitable hydrazine and a suitable tertiary phosphine, more specifically to the compounds di(.mu.-hydrazine-N.sup.1 :N.sup.2)-bis[bis(triphenylphosphine)rhodium (I)]dinitrate and .mu.-3-carbopentazane-N.sup.1, N.sup.4 :N.sup.2, N.sup.5 -bis[bis(triphenylphosphine)rhodium (I)]dinitrate, which are homogenous hydrogenation catalysts and their application in the hydrogenation of the exocyclic methylene group of acid addition salts of 6-demethyl-6-deoxy-6-methylene-5-hydroxytetracycline (methacycline) to prepare .alpha.-6-deoxy-5-hydroxy-tetracycline (doxycycline).


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