The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 20, 1990

Filed:

Feb. 16, 1988
Applicant:
Inventors:

Francis T Boyle, Congleton, GB;

Zbigniew S Matusiak, Cheshire, GB;

Brian S Tait, MacClesfield, GB;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514383 ; 514398 ; 514399 ; 514400 ; 5482622 ; 548335 ; 548341 ; 548342 ;
Abstract

A heterocyclic compound of the formula I, as shown hereafter in these claims in which n is 0 or 1; A is a 1-4C alkylene radical which may optionally bear one or more 1-4C alkyl substituents; R.sup.1 and R.sup.2, which may be the same or different, are each a hydrogen or halogen atom, an amino, carbamoyl, cyano, hydroxy, nitro or sulphamoyl radical, a 1-6C alkyl, halogenoalkyl, alkoxy, halogenoalkoxy, alkylamino, alkylcarbamoyl or alkylsulphamoyl radical, a di(1-6C alkyl)-amino, di(1-6C alkyl)carbamoyl or di(1-6C alkyl)sulphamoyl radical, or a 2-7C alkoxycarbonyl radical; m is an integer of 1 to 5, R.sup.3 is a hydrogen or halogen atom or a 1-6C alkyl or halogenoalkyl radical; and R.sup.4 is a 5-membered aromatic ring heterocyclyl radical containing 2 or 3 nitrogen atoms, or a 6-membered aromatic ring heterocyclyl radical containing 1 or 2 nitrogen atoms, which heterocyclyl radical may bear a 1-6C alkyl substituent; and for those compounds which contain a basic nitrogen atom, the pharmaceutically acceptable acid addition salts thereof together with processes of manufacture and pharmaceutical and veterinary compositions thereof.


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