The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 06, 1990
Filed:
Aug. 02, 1988
Applicant:
Inventors:
Alexander W Chucholowski, Ypsilanti, MI (US);
Mark W Creswell, Chelsea, MI (US);
Bruce D Roth, Ann Arbor, MI (US);
Drago R Sliskovic, Ypsilanti, MI (US);
Assignee:
Warner-Lambert Company, Morris Plains, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ;
U.S. Cl.
CPC ...
514210 ; 514212 ; 5142355 ; 514252 ; 514256 ; 514318 ; 514332 ; 514333 ; 514336 ; 514343 ; 540481 ; 540597 ; 544 82 ; 544131 ; 544295 ; 544296 ; 544333 ; 544357 ; 544360 ; 546187 ; 546193 ; 546256 ; 546268 ; 546281 ; 546284 ;
Abstract
Certain trans-6-[[(substituted)pyridin-3-yl]-alkyl- and alkenyl]tetrahydro-4-hydroxypyran-2-ones and the corresponding ring-opened acids derived therefrom are potent inhibitors of the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) and are useful as hypocholesterolemic and hypolipidemic agents.