The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 1990
Filed:
Apr. 29, 1987
Mitsuyoshi Morii, Yokohama, JP;
Masaharu Ohoka, Yokohama, JP;
Toshihiko Suzuki, Tokyo, JP;
Katsuyuki Suzuki, Hiroshima, JP;
Nobuhiro Kawashima, Sagamihara, JP;
Noriko Morii, Yokohama, JP;
Kunizo Mori, Yokohama, JP;
Mitsui Toatsu Chemicals, Incorporated, Tokyo, JP;
Abstract
A mixture containing a single-chain tissue plasminogen activator (tPA) and/or double-chain tPA is brought into close contact with a column carrying an immobilized Erythrina trypsin inhibitor as an affinity agent. Adsorbed protiens are eluted with eluents having different pHs with or without arginine or benzamidine, so that single-chain tPA is obtained in the eluent with a pH at least 4.5 and double-chain tPA is obtained in the eluent with a pH lower than 4.5.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile