The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 1990
Filed:
Jan. 20, 1987
Andre Dodin, Milly La Foret, FR;
Odile Siffert, Versailles, FR;
Georgette Le Thuillier, Morangis, FR;
Patrice Allard, Paris, FR;
Institut Pasteur, Paris, FR;
Abstract
The invention provides a synthetic peptide which reproduces at least 5 of the 11 amino acids common to the .gamma. chain of sub-unit A of cholera toxin and the .gamma. chain of LT toxin of Escherichia coli. It is preferably constituted by a pentadecapeptide which corresponds to the following formula (I): ##STR1## The process of synthesis is by the step by step construction of the peptide chain starting from the C terminal end of said chain, by the successive fixing of the amino acids which constitute the latter. A novel medicament for the treatment of cholera and infectious gastro-enterites comprises said synthetic peptide as active constituent. A diagnosis agent for cholera and/or infectious gastro-enterites comprises a sequence of nucleotides corresponding to the 5 minimum amino acids of the synthetic peptide.