The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 1990
Filed:
Apr. 28, 1989
Applicant:
Inventors:
David A Swann, Lexington, MA (US);
Bernard P Sullivan, Andover, MA (US);
Gordon Jamieson, Cleveland, GB;
Kenneth R Richardson, Cleveland, GB;
Tarlach Singh, Cleveland, GB;
Assignee:
MedChem Products, Inc., Woburn, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12R / ;
U.S. Cl.
CPC ...
435101 ; 435170 ; 435802 ; 435818 ; 435885 ;
Abstract
Improved overall yields of hyaluronic acid are obtained by controlling the oxygen available for metabolism by a hyaluronic acid producing microorganism. Relatively high oxygen concentrations are made available during the initial exponential growth phase of the cultivated microorganism, until a predetermined growth has been reached. At this time, the available oxygen is limited to stimulate a disproportionately larger production of the desired hyaluronic acid.