The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 23, 1990

Filed:

Dec. 09, 1988
Applicant:
Inventors:

Hiroyuki Yamashita, Fukuoka, JP;

Kunio Okumura, Kanagawa, JP;

Hajime Iizuka, Kanagawa, JP;

Norio Ohto, Kanagawa, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
544405 ; 544406 ; 546256 ; 546279 ; 548379 ;
Abstract

1-Acyl-2-pyrazoline derivatives represented by the formula ##STR1## where R.sup.1 denotes a hydrogen atom, pyridyl group, pyrazinyl group, alkyl group, aryl group, or alkoxy group; and R.sup.2, R.sup.3, and R.sup.4 independently denote a hydrogen atom, furyl group, pyridyl group, alkyl group, or aryl group, are produced by cyclizing by heating an acylhydrazone derivative represented by the formula ##STR2## where R.sup.1, R.sup.2, R.sup.3, and R.sup.4 are defined as above, to produce compounds having useful anti-cerebral edema activity.


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