The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 16, 1990

Filed:

Sep. 22, 1986
Applicant:
Inventors:

Perry W Guinn, Oregon City, OR (US);

Gary N Mills, Gladstone, OR (US);

Assignee:

C. D. Medical, Inc., Miami Lakes, FL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M / ; C12M / ; C12M / ;
U.S. Cl.
CPC ...
435291 ; 435240242 ; 435284 ; 435285 ; 435313 ; 435813 ; 435818 ;
Abstract

An improved bioreactor system for culturing cell products is disclosed in which novel system components are employed to reduce cost and increase reliability. The system includes a simple in-line heater for heating the nutrient fluid, thereby obviating the need for an expensive incubator. Gas bubbles formed during the heating of the nutrient fluid are removed by a novel gas trap that requires no operator intervention. A humidifier humidifies an aerating gas before it is passed through an oxygenator, thereby preventing water within the nutrient fluid from evaporating, with a consequent increase in nutrient fluid concentration. The operation of the humidifier is efficiently combined with that of a nutrient fluid heat exchanger so that a pump is not required to circulate the heat exchanger water bath. The system further includes a valve and pump arrangement whereby fresh nutrient fluid can periodically be introduced and spent nutrient fluid periodically drained without operator intervention. Observation of the color of the nutrient fluid from a concealed location within the bioreactor enclosure is also made possible.


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