The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 1990
Filed:
Aug. 10, 1988
Peter R Luyten, Eindhoven, NL;
Jan A Den Hollander, Eindhoven, NL;
Johannes H Den Boef, Eindhoven, NL;
Johannes J Van Vaals, Eindhoven, NL;
U.S. Philips Corporation, New York, NY (US);
Abstract
The measurement of localized spectra by means of stimulated echoes is known per se. Using three 90.degree. pulses, stimulated echoes are then generated; these pulses are selective or not. However, this technique it is not suitable for measuring good proton spectra of metabolites because the response of the non-bound protons is much greater than the response of the bound protons. In accordance with the invention, a fourth (spatially selective) 180.degree. refocusing pulse is added to a pulse sequence consisting of a 90.degree. non-spatially selective but frequency-selective pulse and two subsequent 90.degree. spatially selective pulses. Thus, a refocused stimulated echo is generated in which the response of the non-bound protons is suppressed and which contains only signals from the chemically bound protons. The proposed methods are particularly suitable for measurements on lactate because of the excellent spectral editing properties.