The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 09, 1990

Filed:

Jul. 10, 1986
Applicant:
Inventors:

Virginio Castagnola, Milan, IT;

E Giuliano Frigerio, Bresso, IT;

Roberto Pellicciari, Perugia, IT;

Aldo Roda, Bologna, IT;

Assignee:

Gipharmex, S.p.A., Milan, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07J / ;
U.S. Cl.
CPC ...
514182 ; 514877 ; 2603971 ;
Abstract

New derivatives of chenodeoxycholic, ursodeoxycholic, cholic and ursocholic acids, bearing a methyl group in the side chain, in an alfa position to the carboxylic group, the corresponding nor- and di-nor- derivatives, and the corresponding conjugates with taurine and glycine, are described. The compounds of the invention are prepared by methylation of the esters with methyl iodide in the presence of lithium-dialkylamides.


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