The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 26, 1989
Filed:
Jun. 10, 1987
Applicant:
Inventor:
Chien-Chin Wu, Wilmington, DE (US);
Assignee:
E. I. Du Pont de Nemours and Company, Wilmington, DE (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ;
U.S. Cl.
CPC ...
514311 ; 514769 ; 514784 ; 514970 ;
Abstract
Freeze-dried pharamceutical compositions of antitumor phenylquinoline carboxylic acids, such as 6-fluoro-2-(2'-fluoro-1'-biphenyl-4-yl)-3-methyl-4-quinolinecarboxylic acid, sodium salt, reconstitutable to stable, aqueous, injectable compositions are provided. These compositions use a stabilization system consisting essentially of bile salt, such as sodium cholate or sodium desoxycholate, and a base or buffer that will provide a pH of about 8.5-11 upon a aqueous reconstitution. Glycine is the preferred buffer.