The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 12, 1989

Filed:

Feb. 17, 1988
Applicant:
Inventors:

Hiroaki Tan, Otake, JP;

Koji Kato, Waki, JP;

Junichi Imuta, Otake, JP;

Noriaki Kihara, Iwakuni, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C78 / ;
U.S. Cl.
CPC ...
564215 ;
Abstract

The present invention provides a cyanoguanidine derivtive which is a precursor for the synthesis of N-cyano-N'-methyl-N'-[2-{(5-methyl-1H-imidazol-4-yl)methylothio}ethyl]-gua nidine (Cimetidine) or its relted compound, which has an action of controlling secretion of acid in the stomach based on the histamine H.sub.2 receptor antagonism and is valuable as a drug for treating gastric ulcer. This cyanoguanidine derivative is prepared by reacting a haloketone derivative with an ammonium salt and a lower fatty acid salt or by reacting other cyanoguanidine derivative with an ammonium salt.


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