The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 28, 1989

Filed:

Jul. 20, 1988
Applicant:
Inventors:

Gabor B Fodor, Morgantown, WV (US);

Kawporn Sussangkarn, Morgantown, WV (US);

Robert W Veltri, Gaithersburg, MD (US);

Assignee:

American Biotechnology Company, Rockville, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514468 ; 514885 ; 549298 ;
Abstract

It has now been discovered that the acid catalyzed Michael reaction products of ascorbic acid and certain selected ketones are useful for their therapeutic activity. More specifically the useful reaction products of the invention are those obtained by reactions of ascorbic acid with .alpha.,.beta. unsaturated alicyclic diketones containing from 5 to 7 carbon atoms. The preferred compounds of the invention may be represented by the formula: ##STR1## wherein n is 1, 2 or 3. The ability of the compounds of this invention to stimulate an immune response has been established by a number of art recognized tests.


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