The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 1989
Filed:
May. 11, 1987
Applicant:
Inventors:
Stuart Schlossman, Newton Center, MA (US);
Chikao Morimoto, Needham, MA (US);
Christopher Rudd, Somerville, MA (US);
Assignee:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C12P / ;
U.S. Cl.
CPC ...
530387 ; 530300 ; 530351 ; 530388 ; 530403 ; 530806 ; 435 68 ; 4352402 ; 424 851 ; 424 858 ; 424 88 ; 935104 ; 935108 ;
Abstract
An essentially purified antigen comprising a protein present in the T-cells of Aotus trivirgatus having molecular weights of 140 KD and 105 KD under reducing conditions and 120 KD and 90 KD under non-reducing conditions, antibodies against this antigen, and a method of using these antibodies to activate T-cells. The antibodies are able to induce T-cell activation in synergy with phorbol myristate acetate alone and with antibody against the T 11.sub.3 epitope of T 11 (CD.sub.2) antigen alone.