The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 1989
Filed:
Oct. 06, 1987
Applicant:
Inventors:
Wolfgang von der Saal, Weinheim, DE;
Jens-Peter Holck, Mannheim, DE;
Alfred Mertens, Schriesheim, DE;
Bernd Muller-Beckmann, Grunstadt, DE;
Lothar Kling, Mannheim, DE;
Assignee:
Boehringer Mannheim GmbH, Mannheim, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; A61K / ;
U.S. Cl.
CPC ...
514338 ; 514253 ; 514254 ; 514255 ; 514397 ; 514365 ; 514372 ; 514374 ; 514378 ; 514383 ; 514381 ; 514362 ; 514363 ; 514269 ; 514241 ; 514317 ; 546271 ; 546199 ; 546144 ; 546148 ; 546153 ; 546167 ; 548221 ; 548222 ; 548241 ; 548159 ; 548209 ; 548212 ; 548334 ; 548325 ; 548329 ; 548327 ; 548181 ; 548214 ; 548206 ; 548233 ; 548215 ; 548245 ; 548246 ; 548255 ; 548266 ; 548252 ; 548254 ; 548251 ; 548127 ; 548128 ; 548133 ; 548131 ; 548134 ; 548135 ; 548137 ; 548136 ; 548143 ; 548328 ; 544405 ; 544324 ; 544322 ; 544333 ; 544238 ; 544148 ; 544212 ; 544180 ; 544179 ; 544370 ; 544235 ; 544237 ;
Abstract
The present invention concerns new 5-alkylbenzimidazoles of the formula: ##STR1## wherein R.sub.1 is a phenyl ring of the formula: ##STR2## or R.sub.1 is naphthyl, heterocycle or a bicyclic heterocycle and R.sub.1 -R.sub.7 are described in claim 1. These compounds are useful for prophylaxis or treatment of heart and circulatory disease especially to increase contractility of the heart, lower blood pressure and/or influence the thrombocyte function and improve the microcirculation.