The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 14, 1989

Filed:

Nov. 19, 1985
Applicant:
Inventors:

Junichi Kajihara, Fuji, JP;

Takao Kiyota, Fuji, JP;

Hiroshi Hayashi, Fuji, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12P / ; C07K / ;
U.S. Cl.
CPC ...
530413 ; 530416 ; 530415 ; 530350 ; 530351 ; 530828 ; 435 68 ; 435 70 ;
Abstract

An aqueous solution containing a physiologically active substance, which is produced by recombinant DNA technique and which has cytotoxic activity against L-M cells and is capable of inducing hemorrhagic necrosis of transplanted Meth A sarcoma in the BALB/c mouse, can be effectively, efficiently purified by column chromatography using a column packed with a dye-bonded crosslinked agarose gel.


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