The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 14, 1989
Filed:
May. 26, 1988
Applicant:
Inventors:
John Kitchin, Eastcote, GB;
Peter C Cherry, South Harrow, GB;
Adrian J Pipe, Greenford, GB;
Andrew J Crame, Greenford, GB;
Alan D Borthwick, London, GB;
Assignee:
Glaxo Group Limited, London, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ;
U.S. Cl.
CPC ...
514215 ; 514411 ; 548430 ;
Abstract
Compounds of the general formula (I) ##STR1## (R is H, alkyl, alkenyl, alkynyl, cycloalkyl, aralkyl or CHO, R.sup.1 and R.sup.2 are independently halogen, alkyl, alkoxy, hydroxyl, cyano, nitro or --NR.sup.3 R.sup.4 where R.sup.3 and R.sup.4 are independently H or alkyl and R.sup.2 may be H) and their salts have selective .alpha..sub.2 -adrenoreceptor antagonist action. The compounds may be prepared by amination of compounds of the general formula (II) ##STR2## (where R.sup.1 and R.sup.2 are as defined above and X is a leaving group.