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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 4879376 B1

PDFFull Text
Date of Patent:
Nov. 07, 1989

Filed:

Jun. 26, 1987

Triterpene saponins having anti-inflammatory, mucolytic and antiedemic

Applicant:
Inventors:

Piero Foresta, Rome, IT;

Orlando Ghirardi, Rome, IT;

Bruno Gabetta, Milan, IT;

Aldo Cristoni, Milan, IT;

Assignees:

Sigma-Tau Industrie Farmaceutiche Riunite S.p.A., Rome, IT;

Inverni Della Beffa Industria Chimico Farmeceutica Derivati Naturali, Milan, IT;

Attorney:

Schneider; Walter H.

Primary Examiner:

Ronald W Griffin

Assistant Examiner:

Nancy S Carson

Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
536 181 ; 536-41 ; 536-5 ; 536-63 ; 536128 ; 4241951 ; 514 26 ; 514 33 ; 514 34 ;
Abstract

Triterpene saponins of formula ##STR1## wherein R.sub.1 is H or OH and R.sub.2 is a tetrasaccharide, or alternatly pentasaccharide, chain have antiinflammatory, mucolytic and antiedemic activities. Said saponins are isolated from roots and bark of Crossopteryx febrifuga, for instance by precipitating them, in form of a complex with cholesterol or sytosterol, from an alcoholic extract of the vegetal material and by partitioning the precipitate between an apolar solvent, which subtracts the complexing agent and a polar solvent in which saponins are soluble.

Find Patent Forward Citations

Foresta, Piero. (1989). Triterpene saponins having anti-inflammatory, mucolytic and antiedemic (U.S. Patent No. 4879376). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/4879376

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