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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 4876191 B1

PDFFull Text
Date of Patent:
Oct. 24, 1989

Filed:

Jul. 14, 1986

Immobilization of biologically active substances with carrier bond

Applicant:
Inventors:

Zeev Hollander, Herzlia, IL;

Beka Salomon, Herzlia Pituach, IL;

Ephraim Katchalski-Katzir, Rehovot, IL;

Assignee:

Ramot University Authority for Applied Research and Industrial, , US;

Attorney:

Fleit, Jacobson, Cohn, Price, Holman & Stern

Primary Examiner:

David M Naff

Int. Cl.
CPC ...
G01N / ; G01N / ; C12P / ; C12N / ;
U.S. Cl.
CPC ...
435-7 ; 435 24 ; 435 26 ; 435 41 ; 435174 ; 435176 ; 435178 ; 435180 ; 436518 ; 436524 ; 436531 ; 436548 ;
Abstract

The invention relates to compositions which are capable of selectively binding a biologically active protein, retaining its activity. Such compositions have essentially three parts, linked together: a water-insoluble carrier, an antibody bound by the carrier and being against the Fc region of an immunoglobulin and an antibody bound thereto which is specific towards the protein which is to be bound to this composition. Proteins of choice are enzymes and isoenzymes such as carboxypeptidas A or isoenzyme 5 of porcine lactate dehydrogenase. Preferably the antibody bound to the carrier is a polyclonal anti-mouse antibody and the antibody bound thereto is a monoclonal mouse antibody. Based on such compositions, there is provided an assay for the quantitative determination of such proteins.

Find Patent Forward Citations

Hollander, Zeev. (1989). Immobilization of biologically active substances with carrier bond (U.S. Patent No. 4876191). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/4876191

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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