The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 1989

Filed:

Aug. 17, 1988
Applicant:
Inventors:

Robert F Baugh, Aurora, CO (US);

Cynthia A Taylor, Denver, CO (US);

Assignee:

Hemotec, Inc., Englewood, CO (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ;
U.S. Cl.
CPC ...
436 69 ; 435 13 ; 436176 ; 436 18 ;
Abstract

An inhibitor of platelet-related procoagulant activity is included in a collection medium into which a whole blood sample is collected. The inhibitor prevents an initial drop in the recalcified activated clotting time measured during an assay test conducted on the whole blood sample collected in citrate in the medium. The discovery of the problem of the initial drop in the activated clotting time and the solution of including the inhibitor of the procoagulant activity is of considerable importance in heparin therapy, since the initial drop in the activated clotting time of heparinized blood is substantial. The inhibitor can be included with a calcium chelating agent in the collection medium. Prostacylin and imidazole, which is an inhibitor of platelet thromboxane A2 synthesis, are effective inhibitors of this platelet-related procoagulant activity.


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