The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 26, 1989

Filed:

Mar. 13, 1987
Applicant:
Inventors:

Ernst Blume, Kriftel, DE;

Wolfgang Schaper, Frankfurt am Main, DE;

Heinz Ehrhardt, Rehling, DE;

Wolfgang Raether, Dreieich, DE;

Walter Dittmar, Hofheim am Taunus, DE;

Heinz Hanel, Bad Homburg, DE;

Burkhard Sachse, Kelkheim, DE;

Assignee:

Hoechst Aktiengesellschaft, Frankfurt am Main, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514340 ; 514341 ; 514399 ; 514397 ; 514383 ; 514255 ; 514326 ; 514274 ; 514367 ; 546276 ; 546278 ; 546210 ; 548341 ; 548335 ; 548262 ; 548336 ; 548202 ; 548203 ; 548247 ; 548179 ; 544370 ; 544366 ; 544318 ; 544315 ; 544333 ;
Abstract

Compounds I ##STR1## where A equals t-butyl or a large number of (substituted) aromatics; Y equals azolyl; or Y equals --X--R.sup.1 where X=oxygen or sulfur and R.sup.1 equals (cyclo)alkyl or (heterocyclic) aryl; or Y equals ##STR2## where R.sup.2 equals (cyclo)alkyl, acetyl or aryl; or Y equals --NR.sup.3 R.sup.4 where R.sup.3 /R.sup.4 is alkyl; or Y equals several nitrogen-containing heterocyclic rings; Z equals OH, alkylcarbonyloxy, hal, alkoxy or benzyloxy; and the salts thereof are effective antimycotics or fungicides. They are obtained by reaction of II ##STR3## with (CH.sub.3).sub.2 ##STR4## and further reaction of the compound IV ##STR5## obtained from this with a nucleophile YM (M=hydrogen or a metal equivalent). The compounds I (where Z=OH) resulting from this can be acylated or alkylated, or converted into I where Z=hal.


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