The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 19, 1989
Filed:
Jun. 30, 1987
Applicant:
Inventors:
Alexander L Johnson, Wilmington, DE (US);
Philip Ma, Chadds Ford, PA (US);
Petrus B Timmermans, Kennett Square, PA (US);
Ruth R Wexler, Wilmington, DE (US);
Assignee:
E. I. Du Pont de Nemours and Company, Wilmington, DE (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; A61K / ; A61K / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514252 ; 514210 ; 514218 ; 514253 ; 514258 ; 514275 ; 514291 ; 514301 ; 514302 ; 514334 ; 514341 ; 540481 ; 540597 ; 540598 ; 540599 ; 540600 ; 540601 ; 544284 ; 544295 ; 544360 ; 544370 ; 546 89 ; 546114 ; 546115 ; 546289 ; 546255 ; 546256 ; 546257 ; 546262 ; 546263 ; 546264 ; 546266 ; 546267 ; 546286 ; 546287 ; 546289 ; 548 95 ;
Abstract
1,4-Dihydropyridine derivatives which combine both calcium agonist and alpha.sub.1 -antagonist activity are useful in treating congestive heart failure. These derivatives are compounds having the formula: ##STR1## wherein Ar, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are defined in the specification.