The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 12, 1989

Filed:

Oct. 23, 1987
Applicant:
Inventors:

Joseph P Balint, Jr, Seattle, WA (US);

Sharon Cochran, Edmonds, WA (US);

Frank R Jones, Edmonds, WA (US);

Harry W Snyder, Edmonds, WA (US);

Assignee:

Imre Corporation, Seattle, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C12N / ; G01N / ;
U.S. Cl.
CPC ...
424 858 ; 424 851 ; 424 852 ; 424 854 ; 424 855 ; 424 856 ; 424 857 ; 530387 ; 436527 ; 435174 ; 502400 ; 502407 ; 604-5 ;
Abstract

Antibody is removed from the blood of patients who are being treated or diagnosed with exogenous macromolecules, such as immunotoxins. As the immunotoxins are foreign antigens, the patient will develop an immune response. The antibodies produced by the immune response upon subsequent immunization with the immunotoxins will interfere with the desired function of the immunotoxins by preventing them from binding with their specific target site. By extracorporeally removing the antibodies, the activity of the immunotoxins can be enhanced.


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