The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 05, 1989
Filed:
May. 15, 1987
Applicant:
Inventors:
William Heggie, Barreiro, PT;
Philip R Page, Sintra, PT;
Ivan Villax, Lisboa Codex, PT;
Michael Hursthouse, Chelmsford, GB;
Richard Somerville, Hornchurch, GB;
Assignee:
Plurichemie Anstalt, Vaduz, LI;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C / ;
U.S. Cl.
CPC ...
2603515 ; 502166 ;
Abstract
The present invention refers to the compounds (.mu.-hydrazine-N.sup.1 :N.sup.2)-bis[bis(triphenylphosphine)-chlororhodium (I)] and di(.mu.-hydrazine-N.sup.1 :N.sup.2)-bis[bis(triphenylphosphine)rhodium (I)] dichloride, which are homogenous hydrogenation catalysts and their application in the hydrogenation of the exocyclic methylene group of acid addition salts of 6-demethyl-6-deoxy-6-methylene-5-hydroxytetracycline (methacycline) to prepare .alpha.-6-deoxy-5-hydroxytetracycline (doxycycline).