The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 1989
Filed:
Jan. 20, 1984
Friedrich Bergter, Jena, DD;
Harald Bocker, Jena, DD;
Ernst-Joachim Bormann, Jena, DD;
Wolfgang Forberg, Jena, DD;
Heinz Fricke, Jena, DD;
Udo Grafe, Jena, DD;
Hans-Helmut Grosse, Jena, DD;
Ingeborg Heller, Jena, DD;
Matthias Hilliger, Jena, DD;
Wolf Junne, Jena, DD;
Hellmut Linde, Jena, DD;
Michael Menner, Ammerbach, DD;
Klaus-Dieter Menzel, Apolda, DD;
Peter-Jurger Muller, Ammerbach, DD;
Gunter Plonka, Jena, DD;
Hans D Pohl, Jena, DD;
Jorg Schneider, Jena, DD;
Heinz Thrum, Jena, DD;
VEB Jenapharm, Jena, DD;
Abstract
A process is disclosed for the fermentative production of the ergotropically effective antibiotic nourseothricin, with which, using different carbohydrate sources and suitable inorganic and organic nitrogen sources as well as different mineral salts, with or without addition of stock substances of the respiratory chain or the intracellular amino acid transport, and through influencing the phosphate substance exchange and avoidance of further limitations with regulated acidity conditions, high concentrations of this antibiotic are cultivated in the culture solution. The recovery of the active substance in the culture solution follows either by chromatographic techniques in the form of salts or through addition of a physiologically compatible adsorbent as mycelium-containing nourseothricin-adsorbate, which preferably can be added to the dosaging of mixed feed agents.