The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 1989

Filed:

Oct. 08, 1986
Applicant:
Inventors:

Keith Reemtsma, New York, NY (US);

Mark A Hardy, Scarsdale, NY (US);

Henry T Lau, New York, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N / ; C12N / ;
U.S. Cl.
CPC ...
435-1 ; 435173 ; 128395 ; 604 49 ;
Abstract

A patient's acceptance of a transplanted organ or tissue from a donor may be enhanced by irradiating donor-specific blood with ultraviolet-B radiation at a dosage of less than 1000 J/M.sup.2 so as to render the blood capable of inducing donor-specific immunological unresponsiveness in the patient, transfusing the irradiated, donor-specific blood into the patient prior to transplanting the organ or tissue into the patient to enhance subsequent acceptance of the organ or tissue by the patient, and thereafter transplanting the organ or tissue into the subject. A patient's acceptance of transplanted organs and tissues can also be enhanced by removing the organ or tissue from the donor and irradiating the organ or tissue to be transplanted with ultraviolet-B radiation at a dosage of less than 1000 J/m.sup.2 so as to enhance acceptance of the transplanted organ or tissue and then transplanting the irradiated organ or tissue into patient.


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