The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 1989
Filed:
Feb. 27, 1984
Applicant:
Inventors:
Patrick W Gray, San Francisco, CA (US);
Ernst H Rinderknecht, San Carlos, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ; C12N / ; C12P / ; C12P / ; C12P / ; C07H / ; C07K / ;
U.S. Cl.
CPC ...
435243 ; 435 68 ; 435 70 ; 435 91 ; 4351721 ; 4351723 ; 4352402 ; 4352523 ; 435320 ; 43525233 ; 530351 ; 536 27 ; 935-9 ; 935 10 ; 935 11 ; 935 27 ; 935 29 ; 935 66 ; 935 72 ;
Abstract
The present invention relates to novel, stable recombinant gamma interferons exhibiting in greater or less degree the antiviral and antiproliferative activity in humans and pH 2 labile properties characteristic of native human gamma interferon. The amino acid sequence of such an interferon comprises, from the N terminus: ##STR1## wherein X is a methionine residue or hydrogen and Y is a glutamine residue or, where X is hydrogen, Y is either a glutamine or a pyroglutamate residue.