The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 01, 1989
Filed:
May. 26, 1987
Applicant:
Inventor:
Paul Schwartz, Rockville, MD (US);
Assignee:
International Pharmaceutical Products, Walnut, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ;
U.S. Cl.
CPC ...
514184 ; 514492 ; 556137 ;
Abstract
Platinum complexes are disclosed in which the platinum cation is coordinated to heterocyclic sulfur compounds as well as monodentate or bidentate amines. The complexes have the formula: ##STR1## wherein L.sub.1 and L.sub.2 are individually ammonia or monodentate amine ligands or L.sub.1 and L.sub.2 together are a bidentate amine ligand, S* is sulfur and R.sub.1 and R.sub.2 taken together with S are thiophene, thiazole, benzothiazole or benzothiophene. These platinum complexes, which have anti-neoplastic activity, are synthesized by reacting sulfonated heterocyclic sulfur compounds with diamines of platinum nitrate.