The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 1989

Filed:

Oct. 13, 1987
Applicant:
Inventors:

Yutaka Koike, Koshigaya, JP;

Masato Nakano, Tokyo, JP;

Shugo Atsuumi, Tokyo, JP;

Seiichi Tanaka, Tokyo, JP;

Hajime Morishima, Tokyo, JP;

Kenji Matsuyama, Kashiwa, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ; C07K / ; C07K / ; C07D / ; C07C / ; C07C / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
514 17 ; 514 18 ; 514 19 ; 530323 ; 530330 ; 530331 ; 530332 ; 548344 ; 560159 ; 564157 ; 564158 ; 564152 ; 564153 ;
Abstract

A 5-substituted amino-4-hydroxy-pentanoic acid derivative having the formula: ##STR1## wherein R.sup.1 is a hydrogen atom or an N-protecting group, R.sup.2, R.sup.3 and R.sup.5 may be any of a variety of groups including the side chains of amino acid residues, R.sup.4 is a hydrogen atom or a lower alkyl group, R.sup.6 is a group which is substituted by one or two hydroxyl groups, and R.sup.7 is any of a variety of groups, including a hydroxyl group, which compounds are renin inhibitors useful as hypotensive drugs, are disclosed.


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