The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 1989

Filed:

Jun. 06, 1986
Applicant:
Inventors:

Richard J Cohen, Newton Highlands, MA (US);

Michael L Broide, Cambridge, MA (US);

Mark S Bowen, Medford, MA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q / ; G01N / ; G01N / ; G01N / ;
U.S. Cl.
CPC ...
435-5 ; 435-7 ; 436517 ; 436518 ; 436520 ; 436523 ; 436529 ; 436531 ; 436533 ; 436805 ; 436815 ; 436816 ; 436817 ; 436823 ; 356336 ; 356338 ;
Abstract

This invention provides a means for determining the concentration of any of a wide range of antibody or antigen molecules with a high degree of specificity, accuracy and sensitivity. Antigen or antibody concentration is determined by effecting an agglutination reaction in a liquid medium and determining the cluster size distribution of agglutinated particles by optical pulse particle size analysis. The measured cluster size distribution then is compared with a standard quantitative relationship between the cluster size distribution and concentration of the antigen or antibody being tested. By this means one may specifically ascertain the absolute concentration of the antigen or antibody in question in the sample being analyzed. In addition to detecting antigen or antibody molecules, the process of this invention can be used to determine the concentration of any substance capable of specifically promoting or inhibiting an agglutination reaction such as viruses, white blood cells or the like.


Find Patent Forward Citations

Cohen, Richard. (1989). Immunoassay employing optical pulse particle size analysis (U.S. Patent No. 4851329). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/4851329

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…