The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 1989
Filed:
Sep. 11, 1986
Applicant:
Inventors:
Janet H Ransom, Germantown, MD (US);
Richard P McCabe, Rockville, MD (US);
Martin V Haspel, Silver Spring, MD (US);
Nicholas Pomato, Frederick, MD (US);
Assignee:
Akzo N.V., Arnhem, NL;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ; A61K / ;
U.S. Cl.
CPC ...
530351 ; 530350 ; 530827 ; 435 68 ; 514-2 ; 514-8 ; 514 21 ; 424 851 ;
Abstract
Leukoregulin is identified, a biologically active lymphokine of molecular weight of about 120,000 to 140,000, with subunits of about 30,000 to 35,000, having the isoelectric focusing pH's of between 4.8 and 5.5 or between 7.5 and 8.3, which has the ability to regulate tumor cell physiology and growth without affecting the growth of normal cells. Methods for stimulating its production by monouclear cells, methods for its isolation and purification, and methods for its therapeutic uses are also disclosed.