The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 18, 1989

Filed:

May. 12, 1987
Applicant:
Inventors:

Hans-Ullrich Hoppe, Hofheim am Taunus, DE;

Susanne Grabley, Konigstein/Taunus, DE;

Hartmut Voelskow, Battersheim am Main, DE;

Merten Schlingmann, Konigstein/Taunus, DE;

Hans P Kraemer, Marburg, DE;

Matthias Wiesner, Mainz, DE;

Joachim Thiem, Munster, DE;

Assignee:

Hoechst Aktiengesellschaft, Frankfurt am Main, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514 27 ; 514 63 ; 514279 ; 536 174 ; 546 14 ; 546 41 ;
Abstract

Streptazoline is reacted with naphthoquinones in a Diels-Alder reaction, and the adduct is then oxidized. The resulting compounds have cytotoxic activity, in particular against leukemia cells, and have an antimicrobial action and act against protozoa.


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